@article{Hoeppener:25,

title = {Unraveling the hierarchical self-assembly of amphiphilic block copolymer-peptide conjugates by tip-enhanced Raman spectroscopy.},

author = { Christiane Höppener and Fabian H. Sobotta and Stephanie Höppener and Volker Deckert and Johannes C. Brendel},

url = {https://pubmed.ncbi.nlm.nih.gov/40519054/},

doi = {10.1002/smll.202502157},

issn = {1613-6829},

year  = {2025},

date = {2025-08-01},

urldate = {2025-08-01},

journal = {Small},

volume = {21},

issue = {32},

pages = {e2502157},

abstract = {Self-assembly of block copolymers in solution provides access to different nanostructures depending on block composition and processing conditions. However, more complex hierarchical nanostructures as found in nature remain challenging to achieve. In this study, the influence of a β-sheet forming tetrapeptide sequence (GFFG) is investigated at the interface of an amphiphilic block copolymer based on poly(butyl acrylate) (PBA) and poly(ethylene oxide) (PEO). Using atomic force microscopy (AFM) and tip-enhanced Raman spectroscopy (TERS), nanoscale insights are provided into the structural organisation and mechanical properties of these hybrid materials. Both the tetrapeptide-containing block copolymer and a control block copolymer without the peptide linker form wormlike micelles in water. However, the incorporation of the peptide linker alters the micelle morphology by increasing the contour length sixfold compared to the control polymer and by altering the mechanical properties of the wormlike micelles. TERS analysis confirms the presence of ordered β-sheet structures at the hydrophilic/hydrophobic interface, which increase the bending stiffness of the micelles. The introduction of additional secondary interactions, such as those induced by the peptide linker, therefore appears as an interesting lever to manipulate the structure formation and mechanical properties block copolymer micelles, opening up interesting design strategies for tailor-made hierarchically structured nanomaterials.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{deinhardt2025sepsis,

title = {Sepsis in patients who are immunocompromised: diagnostic challenges and future therapies},

author = {Stefanie Deinhardt-Emmer and Benjamin G Chousterman and Joerg C Schefold and Stefanie B Flohé and Tomasz Skirecki and Matthijs Kox and Martin S Winkler and Andrea Cossarizza and W Joost Wiersinga and Tom Poll and others},

url = {https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00124-9/fulltext},

doi = {https://doi.org/10.1016/S2213-2600(25)00124-9},

year  = {2025},

date = {2025-01-01},

urldate = {2025-01-01},

journal = {The Lancet Respiratory Medicine},

volume = {13},

number = {7},

pages = {623–637},

publisher = {Elsevier},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hornung:25,

title = {High-fat diet impairs microbial metabolite production and aggravates influenza A infection},

author = { Franziska Hornung and Harini K. SureshKumar and Laura Klement and Yasmina Reisser and Christoph Wernike and Vivien Nischang and Paul M. Jordan and Oliver Werz and Carsten Hoffmann and Bettina Löffler and Stefanie Deinhardt-Emmer},

url = {https://pubmed.ncbi.nlm.nih.gov/40745568/},

doi = {10.1186/s12964-025-02367-w},

issn = {1478-811X},

year  = {2025},

date = {2025-01-01},

urldate = {2025-01-01},

journal = {Cell Communication and Signaling},

volume = {23},

number = {1},

pages = {359},

publisher = {Springer},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{hoppener2024tip,

title = {Tip-enhanced Raman scattering},

author = {Christiane Höppener and Javier Aizpurua and Huan Chen and Stefanie Gräfe and Ado Jorio and Stephan Kupfer and Zhenglong Zhang and Volker Deckert},

url = {https://www.nature.com/articles/s43586-024-00323-5},

doi = {https://doi.org/10.1038/s43586-024-00323-5},

year  = {2024},

date = {2024-01-01},

urldate = {2024-01-01},

journal = {Nature Reviews Methods Primers},

volume = {4},

number = {1},

pages = {47},

publisher = {Nature Publishing Group UK London},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{schulz2023influenza,

title = {Influenza virus-induced paracrine cellular senescence of the lung contributes to enhanced viral load},

author = {Luise Schulz and Franziska Hornung and Antje Häder and Lukáš Radosa and Axel A Brakhage and Bettina Löffler and Stefanie Deinhardt-Emmer},

url = {https://pmc.ncbi.nlm.nih.gov/articles/PMC10389813/},

doi = {https://doi.org/10.14336/AD.2023.0310},

year  = {2023},

date = {2023-01-01},

urldate = {2023-01-01},

journal = {Aging and disease},

volume = {14},

number = {4},

pages = {1331},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{hoppener2023inside,

title = {Inside Block Copolymer Micelles—Tracing Interfacial Influences on Crosslinking Efficiency in Nanoscale Confined Spaces},

author = {Christiane Höppener and Johanna K Elter and Felix H Schacher and Volker Deckert},

url = {https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202206451},

doi = {https://doi.org/10.1002/smll.202206451},

year  = {2023},

date = {2023-01-01},

urldate = {2023-01-01},

journal = {Small},

volume = {19},

number = {20},

pages = {2206451},

publisher = {Wiley Online Library},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{DeckertGaudig:23,

title = {Identification of RNA-containing virus particles using a triple correlative morphological and microscopic approach},

author = {Tanja Deckert-Gaudig and Xiaobin Yao and Erwan Darussalam and Franziska Hornung and Pablo Carravilla and Ziliang Zhao and Kourosh Rezaei and Christian Eggeling and Stefanie Deinhardt-Emmer and Volker Deckert},

url = {https://chemrxiv.org/engage/chemrxiv/article-details/64e8c60279853bbd786af71a},

doi = {10.26434/chemrxiv-2023-b9mr1},

year  = {2023},

date = {2023-01-01},

urldate = {2023-01-01},

journal = {accepted in: J Translat Med},

publisher = {American Chemical Society (ACS)},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{deinhardt2021early,

title = {Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and the correlation with tissue damage},

author = {Deinhardt-Emmer, Stefanie and Wittschieber, Daniel and Sanft, Juliane and Kleemann, Sandra and Elschner, Stefan and Haupt, Karoline Frieda and Vau, Vanessa and Häring, Clio and Rödel, Jürgen and Henke, Andreas and Ehrhardt, Christina and Bauer, Michael and Philipp, Mike and Gaßler, Nikolaus and Nietzsche, Sandor and Löffler, Bettina and Mall, Gita},

url = {https://elifesciences.org/articles/60361},

doi = {https://doi.org/10.7554/eLife.60361},

year  = {2021},

date = {2021-01-01},

urldate = {2021-01-01},

journal = {Elife},

volume = {10},

pages = {e60361},

publisher = {eLife Sciences Publications, Ltd},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Deckert:20,

title = {Laser spectroscopic technique for direct identification of a single virus I: FASTER CARS},

author = { Volker Deckert and Tanja Deckert-Gaudig and Dana Cialla-May and Jürgen Popp and Roland Zell and Stefanie Deinhard-Emmer and Alexei V Sokolov and Zhenhuan Yi and Marlan O Scully},

url = {https://www.pnas.org/doi/abs/10.1073/pnas.2013169117},

doi = {10.1073/pnas.2013169117},

year  = {2020},

date = {2020-01-01},

urldate = {2020-01-01},

journal = {Proc Natl Acad Sci},

volume = {117},

issue = {45},

pages = {27820–27824},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Olschewski:15,

title = {A manual and an automatic TERS based virus discrimination},

author = { Konstanze Olschewski and Evelyn Kämmer and Stephan Stöckel and Thomas Bocklitz and Tanja Deckert-Gaudig and Roland Zell and Dana Cialla-May and Karina Weber and Volker Deckert and Jürgen Popp},

url = {https://pubmed.ncbi.nlm.nih.gov/25686406/},

doi = {10.1039/c4nr07033j},

issn = {2040-3372},

year  = {2015},

date = {2015-03-01},

urldate = {2015-03-01},

journal = {Nanoscale},

volume = {7},

issue = {10},

pages = {4545–4552},

keywords = {},

pubstate = {published},

tppubtype = {article}

}