Analysis of microRNA expression reveals convergent evolution of the molecular control of diapause in annual killifishes

Identification and optimization of a small molecule inhibitor of the ovarian tumor protease of the Crimean-Congo hemorrhagic fever virus

Enhanced efficiency of the microsomal prostaglandin E2 synthase-1 inhibitor AGU661 in human whole blood by encapsulation into PLGA-based nanoparticles

Crossover operators for molecular graphs with an application to virtual drug screening

Self-supervised machine learning methods for protein design improve sampling but not the identification of high-fitness variants

AnchoRNA: Full virus genome alignments through conserved anchor regions

Unraveling the hierarchical self-assembly of amphiphilic block copolymer-peptide conjugates by tip-enhanced Raman spectroscopy

High-fat diet impairs microbial metabolite production and aggravates influenza A infection

Matching drug and polymer for efficient delivery of anti-inflammatory drugs: PLGA, polyesteramides, and acetalated dextran

Deciphering respiratory viral infections by harnessing organ-on-chip technology to explore the gut-lung axis

Cholesterol allosteric modulation of the oxytocin receptor

Persistence, spillover, and evolution of co-occurring lineages of lymphocytic choriomeningitis virus

diffONT: Predicting methylation-specific PCR biomarkers based on nanopore sequencing data for clinical application

Chemical characteristics vectors map the chemical space of natural biomes from untargeted mass spectrometry data

Raman spectroscopy can identify acute and persistent biochemical changes in leukocytes from patients with COVID-19 and non-COVID-19-associated sepsis

VirJenDB: A FAIR (meta)data and analysis platform for all viruses

Dynamont: A Comprehensive Cross-Species Comparison of ONT Segmentation Tools

Mild Oxidation of Plant Polyphenols Yields Modular Nanoparticle-Forming Materials with Drug Loading Capabilities

Selective activation of dynamics in kinetically frozen supramolecular polymer bottlebrush assemblies

Computational engineering of siderocalin to modulate its binding affinity to the antihypertension drug candesartan

An RNA sponge directs the transition from feast to famine in Caulobacter crescentus

Surface-enhanced Raman spectroscopy: a half-century historical perspective

Analysis of metabolomics and transcriptomics data to assess interactions in microalgal co-culture of Skeletonema marinoi and Prymnesium parvum

Organ-on-chip models for infectious disease research

HyperMPNN-A general strategy to design thermostable proteins learned from hyperthermophiles

Combining machine learning with structure-based protein design to predict and engineer post-translational modifications of proteins

Combining Rosetta sequence design with protein language model predictions using evolutionary scale modeling (ESM) as restraint

Selective uptake into inflamed human intestinal tissue and immune cell targeting by wormlike polymer micelles

Importations of SARS-CoV-2 lineages decline after nonpharmaceutical interventions in phylogeographic analyses

Aspergillus fumigatus-derived gliotoxin impacts innate immune cell activation through modulating lipid mediator production in macrophages

PEG-Lipid-PLGA Hybrid Particles for Targeted Delivery of Anti-Inflammatory Drugs

Influenza A virus selectively elevates prostaglandin E2 formation in pro-resolving macrophages

Comprehensive transcriptome analysis reveals altered mRNA splicing and post-transcriptional changes in the aged mouse brain

MicrobioRaman: An open-access web repository for microbiological Raman spectroscopy data

Backbone chemical shift and secondary structure assignments for mouse siderocalin

Strategies of rational and structure-driven vaccine design for Arenaviruses

Raman-Activated, Interactive Sorting of Isotope-Labeled Bacteria

PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis

Endogenous Bornavirus-like elements in bats: Evolutionary insights from the conserved riboviral L-gene in microbats and its antisense transcription in Myotis daubentonii

The global RNA–RNA interactome of Klebsiella pneumoniae unveils a small RNA regulator of cell division

Evaluation of SARS-CoV-2-Specific IgY Antibodies: Production, Reactivity, and Neutralizing Capability against Virus Variants

Engineering extracellular vesicles to transiently permeabilize the blood-brain barrier

Comprehensive survey of conserved RNA secondary structures in full-genome alignment of hepatitis C virus

Nanobody-mediated neutralization of candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesis

Genome-wide profiling of Hfq-bound RNAs reveals the iron-responsive small RNA RusT in Caulobacter crescentus

Ethoxy acetalated dextran nanoparticles for drug delivery: A comparative study of formulation methods

Identification of RNA-containing virus particles using a triple correlative morphological and microscopic approach

Contribution of radixin and ezrin to the maintenance of hepatocytes' excretory function in health and disease

NFDI4Microbiota – national research data infrastructure for microbiota research

Tuning the corona-core ratio of polyplex micelles for selective oligonucleotide delivery to hepatocytes or hepatic immune cells

Importations of SARS-CoV-2 lineages decline after nonpharmaceutical interventions in phylogeographic analyses

Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein

The International Virus Bioinformatics Meeting 2023

Interplay of thermodynamics and evolution within the ternary ligand-GPCR-G protein complex

Genome structure, life cycle, and taxonomy of coronaviruses and the evolution of SARS-CoV-2

Microbial degradation and assimilation of veratric acid in oxic and anoxic groundwaters

Guided-deconvolution for correlative light and electron microscopy

Mystery of fatal 'staggering disease' unravelled: Novel rustrela virus causes severe meningoencephalomyelitis in domestic cats

Identification of altered miRNAs and their targets in placenta accreta

Polymer-based particles against pathogenic fungi: A non-uptake delivery of compounds

Simple, fast and convenient magnetic bead-based sample preparation for detecting viruses via Raman-spectroscopy

Investigating biochemical and structural changes of glycated collagen using multimodal multiphoton imaging, Raman spectroscopy, and atomic force microscopy

Intestinal epithelial barrier integrity investigated by label-free techniques in ulcerative colitis patients

Navigating the landscape: A comprehensive review of current virus databases

Functional comparisons of the virus sensor RIG-I from humans, the microbat Myotis daubentonii, and the megabat Rousettus aegyptiacus, and their response to SARS-CoV-2 infection

Quantitative analysis of peroxisome tracks using a Hidden Markov Model

Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision

Computational modeling and prediction of deletion mutants

Targeting of phagolysosomes containing conidia of the fungus Aspergillus fumigatus with polymeric particles

Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021

Women in the European Virus Bioinformatics Center

The International Virus Bioinformatics Meeting 2022

Efficient gene delivery of tailored amphiphilic polypeptides by polyplex surfing

Analysis of HDACi-coupled nanoparticles: Opportunities and challenges

Phenotypic differentiation of autotrophic and heterotrophic bacterial cells using Raman-D2O labeling

Structural comparative modeling of multi-domain F508del CFTR

Taxonomic classification of DNA sequences beyond sequence similarity using deep neural networks

Small integral membrane protein 10 like 1 downregulation enhances differentiation of adipose progenitor cells

Carbon fixation rates in groundwater similar to those in oligotrophic marine systems

Raman spectroscopic cellomics for the detection of SARS-CoV-2-associated neutrophil activation after TNF-α stimulation

The genomic and transcriptional landscape of primary central nervous system lymphoma

Epitope-focused immunogen design based on the Ebolavirus glycoprotein HR2-MPER region

Microbial community functioning during plant litter decomposition

Structural and biochemical changes in pericardium upon genipin cross-linking investigated using nondestructive and label-free imaging techniques

Draft genome assembly and sequencing dataset of the marine diatom Skeletonema cf. costatum RCC75

Computational structure prediction for antibody-antigen complexes from hydrogen-deuterium exchange mass spectrometry: Challenges and outlook

Targeted suppression of peptide degradation in Ag-based surface-enhanced Raman spectra by depletion of hot carriers

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

Age-dependent expression changes of circadian system-related genes reveal a potentially conserved link to aging

Activity and electron donor preference of two denitrifying bacterial strains identified by Raman gas spectroscopy

BEXIS2: A FAIR-aligned data management system for biodiversity, ecology and environmental data

The economical lifestyle of CPR bacteria in groundwater allows little preference for environmental drivers

Raman Spectroscopy and imaging in bioanalytics

EpiDope: A deep neural network for linear B-cell epitope prediction

SARS-CoV-2 causes severe epithelial inflammation and barrier dysfunction

Ligand-binding and -scavenging of the chemerin receptor GPR1

Cyclic analogues of the chemerin C-terminus mimic a loop conformation essential for activating the chemokine-like receptor 1

Structural perspective on ancient neuropeptide Y-like system reveals hallmark features for peptide recognition and receptor activation

ITN-VIROINF: Understanding (harmful) virus-host interactions by linking virology and bioinformatics

Draft Genome Sequence of Bordetella sp. Strain FB-8, Isolated from a Former Uranium Mining Area in Germany

Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas

Computational strategies to combat COVID-19: Useful tools to accelerate SARS-CoV-2 and coronavirus research

RosettaCM for antibodies with very long HCDR3s and low template availability

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

Ethoxy acetalated dextran-based nanocarriers accomplish efficient inhibition of leukotriene formation by a novel FLAP antagonist in human leukocytes and blood

Biocompatible sulfated valproic acid-coupled polysaccharide-based nanocarriers with HDAC inhibitory activity

Monitoring deuterium uptake in single bacterial cells via two-dimensional Raman correlation spectroscopy

VIDHOP, viral host prediction with deep learning

BERTax: Taxonomic classification of DNA sequences with Deep Neural Networks

Monoclonal antibodies specific for the hemagglutinin-neuraminidase protein define neutralizing epitopes specific for Newcastle disease virus genotype 2.VII from Egypt

Stealth effect of short polyoxazolines in graft copolymers: Minor changes of backbone end group determine liver cell-type specificity

Rates of primary production in groundwater rival those in oligotrophic marine systems

Virus bioinformatics

Targeted delivery of a phosphoinositide 3-kinase γ inhibitor to restore organ function in sepsis

Modeling immunity with Rosetta: Methods for antibody and antigen design

SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells

Bolstering fitness via CO2 fixation and organic carbon uptake: Mixotrophs in modern groundwater

Characterization of SARS-CoV-2 infection clusters based on integrated genomic surveillance, outbreak analysis and contact tracing in an urban setting

Swarm Learning for decentralized and confidential clinical machine learning

Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress

Pan-cancer analysis of whole genomes

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Mixotrophic iron-oxidizing Thiomonas isolates from an acid mine drainage-affected creek

Predicting susceptibility to SARS-CoV-2 infection based on structural differences in ACE2 across species

The repertoire of mutational signatures in human cancer

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19

Divergent mutational processes distinguish hypoxic and normoxic tumours

Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Inferring structural variant cancer cell fraction

Iron is not everything: Unexpected complex metabolic responses between iron-cycling microorganisms

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Laser spectroscopic technique for direct identification of a single virus I: FASTER CARS

Co-infection with S. aureus after influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model

Nanoscopy on the Chea (i) p

Regulation outside the box: New mechanisms for small RNAs

Criteria for appraisal and assessment of research data upon submission to a data repository

The evolutionary history of 2,658 cancers

Genomic basis for RNA alterations in cancer

Switching fatty acid metabolism by an RNA-controlled feed forward loop

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

Eleven grand challenges in single-cell data science

Present and future of surface-enhanced Raman scattering

Patterns of somatic structural variation in human cancer genomes

Sex differences in oncogenic mutational processes

Influence of carbon sources on quantification of deuterium incorporation in heterotrophic bacteria: A Raman-stable isotope labeling approach

A comprehensive annotation and differential expression analysis of short and long non-coding RNAs in 16 bat genomes

Inclusion of Oxford Nanopore long reads improves all microbial and viral metagenome-assembled genomes from a complex aquifer system

Integrative pathway enrichment analysis of multivariate omics data

RNA-mediated control of cell shape modulates antibiotic resistance in Vibrio cholerae

Pathway and network analysis of more than 2500 whole cancer genomes

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig

Staphylococcus aureus lung infection results in down-regulation of surfactant protein-A mainly caused by pro-inflammatory macrophages

Flotillin-dependent membrane microdomains are required for functional phagolysosomes against fungal infections

Severe COVID-19 is marked by a dysregulated myeloid cell compartment

Entwicklung eines FDM-Coachings für Arbeitsgruppen

Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity

Combined burden and functional impact tests for cancer driver discovery using DriverPower

Genomic footprints of activated telomere maintenance mechanisms in cancer

Hydroxamic Acids Immobilized on Resins (HAIRs): Synthesis of dual-targeting HDAC inhibitors and HDAC degraders (PROTACs)

Tissue-specific gene expression changes are associated with aging in mice

Butler enables rapid cloud-based analysis of thousands of human genomes

Comprehensive molecular characterization of mitochondrial genomes in human cancers

The landscape of viral associations in human cancers

High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

Conserved aging-related signatures of senescence and inflammation in different tissues and species

Infectious entry of Merkel cell polyomavirus

Extracellular conformational changes in the capsid of human papillomaviruses contribute to asynchronous uptake into host cells

Ultrasensitive and towards single molecule SERS: General discussion

The evolution of COP9 signalosome in unicellular and multicellular organisms

Characterization of pH dependent Mn(II) oxidation strategies and formation of a bixbyite-like phase by Mesorhizobium australicum T-G1

Single virus detection by means of atomic force microscopy in combination with advanced image analysis

Signatures of mutational processes in human cancer

Oxygen minimum zones harbour novel viral communities with low diversity

RNAcentral: A vision for an international database of RNA sequences

Biochemical imaging below the diffraction limit–probing cellular membrane related structures by tip-enhanced Raman spectroscopy (TERS)

A topological approach to chemical organizations

Raman to the limit: Tip-enhanced Raman spectroscopic investigations of a single tobacco mosaic virus

Identification and analysis of functional elements in 1 % of the human genome by the ENCODE pilot project

On the way to nanometer-sized information of the bacterial surface by tip-enhanced Raman spectroscopy