The Integrated Research Training Group (IRTG) of CRC VirusREvolution translates the consortium’s mission into a structured doctoral programme. It trains our >25 early-career researchers (ECRs) in hypothesis-driven virology, bioinformatics, and photonics, complemented by transferable skills in ethics, data management, communication, leadership, and mental health awareness. The programme follows the Salzburg Principles and the UniWinD competence framework. Through modular, level-specific courses and innovative teaching formats such as hackathons and flipped classrooms, the IRTG fosters creativity, autonomy, interdisciplinarity, and emphasizes the scientific independence of its members. Distinctive elements include interdisciplinary PhD–PhD tandems that bridge virology, bioinformatics, and photonics, ensuring both cross-disciplinary collaboration and the inclusion of externally based PhDs. All supervisors participate in mandatory training on supervision, diversity, and mental health awareness. Individual Development Plans (IDPs) guide scientific and personal skill development, while continuous evaluation through Thesis Advisory Committee (TAC) reports, feedback surveys, and doctoral representation ensures programme quality. Integration within the Jena Graduate Academy (JGA) and collaboration with partner graduate schools secure institutional alignment and access to advanced training opportunities. The IRTG builds a collaborative, inclusive, and internationally visible training culture, preparing graduates for careers in academia, industry, and beyond.